Mini-Review: Morphology of Pyramidal Neurons in Schizophrenia

Recommended Reading

Mini-Review: Dendritic Spine Density

Background Information for Mini-Reviews

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In the previous mini-review we explored the differences in dendritic spine density of pyramidal neurons in the brains of people with schizophrenia compared to those without schizophrenia. Due to the severity of this dendritic spine deficiency it seemed unlikely that these pyramidal neurons were otherwise unaffected. Having explored this area of research further, it has become clear that not only do the pyramidal neurons of people with schizophrenia present with fewer spines than those without the illness, but these neurons also show deficiencies in soma size, dendrite length, and dendritic branching.